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Double Chamber Plethysmography

Non-invasive Airway Mechanics

The EMMS non-invasive airway mechanics system uses a classic Pennock style double-chamber plethysmograph to measure nasal and thoracic flow. The animal is placed in a double-chamber plethysmograph (eg. PLY 230 for guinea pig), and is restrained in the chamber with a rubber neck collar. This neck collar also provides an airtight seal between the thoracic and nasal chambers. Flow in the two chambers is measured across two pneumotachographs in the plethysmograph wall. A bias flow air supply is used to prevent build-up of CO2 in the plethysmograph, and may also be used to pull aerosol through the nasal chamber.

Double Chmaber Plethysmograph

EMMS Double Chamber Plethysmographs in Conical and Sloped Front configuration.


Parameters Measured

  • Specific Airway Resistance
  • Specific Airway Conductance
  • Tidal Volume
  • Minute Volume
  • Time of Inspiration
  • Time of Expiration
  • Peak Expiratory Flow
  • Peak Inspiratory Flow
  • Respiratory Rate
  • Explanations and more parameters


  • Up to 8 animals monitored simultaneously
  • Completely non-invasive
  • No anaesthesia required
  • Aerosol can be administered via the nasal chamber


  • Chronic studies
  • Suitable for long-term measurements


 EMMS Solutions  
eSpira™ Forced Manoeuvres
Resistance and Compliance
Whole Body Plethysmography
Head-Out Plethysmography
Double Chamber Plethysmography
Cardiac Action Potential
ECG Monitoring
Custom Solutions
(c) EMMS